Enterobacteria of the neonate. Normal colonization and antibiotic-induced selection.

Enteric dysbiosis promotes antibiotic-resistant bacterial infection: systemic dissemination of resistant and commensal bacteria through epithelial transcytosis.

Antibiotic usage promotes intestinal colonization of antibiotic-resistant bacteria. However, whether resistant bacteria gain dominance in enteric microflora or disseminate to extraintestinal viscera remains unclear. Our aim was to investigate temporal diversity changes in microbiota and transepithelial routes of bacterial translocation after antibiotic-resistant enterobacterial colonization. Mi...

Causes, consequences, and perspectives in the variations of intestinal density of colonization of multidrug-resistant enterobacteria

The intestinal microbiota is a complex environment that hosts 10(13) to 10(14) bacteria. Among these bacteria stand multidrug-resistant enterobacteria (MDRE), which intestinal densities can substantially vary, especially according to antibiotic exposure. The intestinal density of MDRE and their relative abundance (i.e., the proportion between the density of MDRE and the density of total enterob...

Comparison of the Umbilical Cord Bacterial Colonization in Newborn Infants Rooming in with Mothers and Neonates Admitted to Neonatal Intensive Care Unit

Background Bacterial colonization during and shortly after birth are common in newborn infants. The aim of this study was to determine the umbilical cord bacterial colonization in newborn infants rooming in with mothers and neonates admitted to neonatal intensive care unit (NICU). Materials and Methods In a cross-sectional study, 180 newborn infants were studied in three groups including: newbo...

The Prevalence of Group B Streptococcus Colonization in Iranian Pregnant Women and Its Subsequent Outcome

Effects of intrapartum penicillin prophylaxis on intestinal bacterial colonization in infants.

Early-onset group B streptococcal (GBS) infections remain a leading cause of morbidity and mortality in infants. To prevent the vertical transmission of GBS and neonatal GBS infection, guidelines recommend intrapartum penicillin or amoxicillin prophylaxis. This intrapartum antibiotic prophylaxis (IAP) is suspected to favor colonization by antibiotic-resistant bacteria. However, the effects of t...